Houston Astros vs. Washington Nationals

The Houston Astros host the Washington Nationals at Daikin Park (renamed from Minute Maid Park ahead of the 2025 season) as part of a three-game series in early May 2027. It's a regular-season interleague-style matchup pitting the Astros, a perennial AL West contender since their 2017 and 2022 World Series titles, against a Nationals club still rebuilding its core since trading away pieces of its 2019 championship roster. Daikin Park's retractable roof keeps games climate-controlled regardless of Houston's early-May heat and humidity, and the stadium's Crawford Boxes in left field remain a signature feature for fans chasing home run balls. As with any MLB date scheduled this far out, the exact game time — and in this case, the precise day within the series — isn't pinned down beyond the announced series window, so travelers should confirm first pitch closer to the date.